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Diseases

Diseases

We are living in an interconnected world where an outbreak of infectious disease is just a plane ride away. As a global leader in research, CDC provides technical expertise and engagement in on-the-ground programs to help detect diseases, break the cycle of transmission, and to lower the mortality rate of those living with disease.

Vietnam - Influenza (flu)

NEED

Vietnam is at high risk for emerging influenza viruses with pandemic potential.

INTERVENTION

Strengthen the surveillance system for Severe Viral Pneumonia, the primary system for detection of novel influenza viruses and other emerging respiratory pathogens in humans


Estimate the economic burden of influenza in Vietnam


Introduce seasonal flu vaccine and implement national scale up

TYPE OF ACTIVITIES 

Disease specific (Influenza)

APPROXIMATE FUNDING NEED

$3.8 million

Vietnam - Tuberculosis (TB)

NEED

Among 30 high-burden TB countries in the world, Vietnam ranks sixteenth, with an estimated 124,000 new TB patients in 2017 alone, including 7,100 cases of multidrug-resistant TB and 12,000 TB-related deaths.

INTERVENTION

Rapidly reduce TB burden in Ho Chi Minh City and other priority provinces through demonstration projects and scale up


Prevent TB among US-bound immigrants and refugees from Vietnam

TYPE OF ACTIVITIES 

Disease specific (TB)

APPROXIMATE FUNDING NEED

$2.3 million

Haiti - Cholera

NEED

While Haiti is recording the lowest levels of suspected cholera cases since 2011, cholera remains a public health threat and gains made since the last outbreak must be maintained.

INTERVENTION

Interrupt cholera transmission by enhancing Haiti’s laboratory cholera surveillance and response capacity and implementing water, sanitation and hygiene projects

TYPE OF ACTIVITIES 

Disease specific (Cholera)

APPROXIMATE FUNDING NEED

$4.1 million

Haiti - Neglected tropical diseases (NTDs)

NEED

Lymphatic filariasis is on the cusp of elimination in Haiti, one of only four countries in the Americas where the disease remains.

INTERVENTION

Eliminate lymphatic filariasis through mass drug administration, morbidity management and disability prevention and surveillance

ACTIVITIES 

Disease specific (Neglected tropical disease)

APPROXIMATE FUNDING NEED

$15 million

Sierra Leone - Malaria

NEED

Indoor bites from mosquitoes account for 80%–100% of overnight malaria transmission in Africa, and while built-environment modifications were once staples of malaria vector control, they have been neglected for at least the past two decades.

INTERVENTION

Implement a pilot study to assess the impact of new screening strategies on malaria vector control

TYPE OF ACTIVITIES 

Disease specific (Malaria)

APPROXIMATE FUNDING NEED

$232,000

Funding Needed
$25,432,000
diseases
Viet Nam
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Emergency Preparedness

Emergency Preparedness

With 70 percent of countries still not fully prepared to respond to a public health emergency, it is more likely that infectious diseases will take root and spread across borders. Fast and effective response can stop a local outbreak from becoming a global epidemic.

The world has committed to building public health emergency operations centers capable of activating a coordinated response within 120 minutes of the identification of a public health emergency. CDC experts collaborate with the international community to improve their ability to prepare and respond to emergencies.

Haiti

NEED

Hit by multiple natural disasters over the past decade, preparedness and emergency response capacity are critical in Haiti.

INTERVENTION

Fully operationalize an Emergency Operations Center in Haiti by finalizing interoperability of information technology and purchasing equipment, developing table top exercises and continuing training of EOC personnel

TYPE OF ACTIVITIES 

Emergency preparedness

APPROXIMATE FUNDING NEED

$464,000

Sierra Leone

NEED

Preserving the informational legacy of the Ebola epidemic gives a unique opportunity to analyze the mortality impact of Ebola, improve future Ebola responses and build research capacity in Sierra Leone.

INTERVENTION

Improve secure access to the Sierra Leone Ebola Database

TYPE OF ACTIVITIES 

Emergency preparedness

APPROXIMATE FUNDING NEED

$900,000

Sierra Leone

NEED

Operational support of the National EOC will cease in June 2019 and additional planning is needed to ensure this support is successfully transitioned to the MoHS.

INTERVENTION

Build country ownership for the National Emergency Operations Center

TYPE OF ACTIVITIES 

Emergency preparedness

APPROXIMATE FUNDING NEED

$750,000

Funding Needed
$2,114,000
Emergencypreparedness
Sierra Leone
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Workforce Development

Workforce Development

Central to public health workforce development is CDC’s Field Epidemiology Training Program (FETP), which trains field epidemiologists in developing countries. Graduates of these programs have the skills to collect, analyze and interpret disease information, using evidence to take quick action and save lives.

Individual countries and ministries of health own the program, which are tailored to meet the needs of each country, recognizing differences in disease burdens, cultures, priorities, partners, capacities and public health systems.

India

NEED

A key priority of the Global Health Security Agenda and a major strategic objective of CDC India is the development of strong cadres of public health workers.

INTERVENTION

Expand the India Field Epidemiology Training Program to increase country capacity for disease surveillance and outbreak investigation

TYPE OF ACTIVITIES 

Workforce development

APPROXIMATE FUNDING NEED

$1.5 million

Vietnam

NEED

Key to addressing the challenges of outbreak detection, prevention and response in Vietnam is the development of a public health workforce with solid practical epidemiological skills.

INTERVENTION

Expand the Field Epidemiology Training Program in Vietnam

TYPE OF ACTIVITIES 

Workforce development

APPROXIMATE FUNDING NEED

$1.6 million

Haiti

NEED

Improve Haiti's public health workforce capacity in business administration to ensure proper management of public health projects.

INTERVENTION

Support the Field Epidemiology Training Program and provide community health workers with surveillance training and training in business management software

TYPE OF ACTIVITIES 

Workforce development

APPROXIMATE FUNDING NEED

$4.6 million

Sierra Leone

NEED

Currently, the Field Epidemiology Training Program relies on technical support from international mentors to maintain program quality.

INTERVENTION

Strengthen the Field Epidemiology Training Program so that graduates can serve as mentors for future cohorts

TYPE OF ACTIVITIES 

Workforce development

APPROXIMATE FUNDING NEED

$3.1 million

Funding Needed
$10,800,000
Workforce development
Haiti
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Laboratory

Laboratory

In today’s healthcare system, 70 percent of medical decisions depend on laboratory test results. Strong clinical laboratories provide the foundation for accurate and timely disease diagnosis, prevention and control to improve public health and safety.

CDC improves laboratory quality and safety, informatics and data science, and workforce competencies to safeguard both patient and public health.

Nigeria

NEED

Nigeria has more malaria cases than any other country, with a prevalence of 27 percent among children under five years of age.

INTERVENTION

Implement proactive community detection of malaria, pneumonia and diarrhea

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$5 million

India

NEED

Acute febrile illness affects thousands of people every year in India, leading to severe morbidity and mortality.

INTERVENTION

Establish a tiered diagnostic system for seven acute febrile illness pathogens among hospitals across the country

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$880,000

Vietnam

NEED

The ministry of health has limited capacity to detect unusual or emerging pathogens in the course of outbreak investigations.

INTERVENTION

Establish a national public health reference laboratory network with the capacity for advanced diagnostic testing that produces credible results

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$1.2 million

Haiti

NEED

In order to accurately identify and detect pathogens, Haiti’s laboratory quality systems need improvement.

INTERVENTION

Improve pathogen detection by building public health laboratory capacity through expansion of Haiti’s specimen storage, operationalizing the country’s National Specimen Referral Network and building national and subnational laboratory capacity

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$2.9 million

Sierra Leone

NEED

Renovations, equipment, supplies and workforce development are needed for the Central Public Health Laboratory (CPHRL) to serve the five reference laboratories within Sierra Leone and provide leadership and guidance within the MOHS public health systems.

INTERVENTION

Sustainably renovate and operationalize the CPHRL

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$2 million

Funding Needed
$11,980,000
Laboratory
India
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Surveillance

Surveillance

A pathogen can travel around the globe to major cities in as little as 36 hours. CDC experts are on the frontlines fighting diseases to protect Americans in the United States and abroad. CDC works around the clock to get the right information into the right hands at the right time.

CDC’s global activities protect Americans from major health threats, including Ebola, influenza, tuberculosis (TB) and malaria. CDC monitors disease outbreaks 24/7 around the world to prevent regional and global health crises that affect health, security and economic stability abroad and at home.

Nigeria

NEED

The existing surveillance systems in Nigeria are often fragmented, disease specific, inconsistent and in need higher quality control.

INTERVENTION

Establish an integrated diagnostics and surveillance system

TYPE OF ACTIVITIES 

Surveillance

APPROXIMATE FUNDING NEED

$2.1 million

Nigeria

NEED

A surveillance and response clinical telecommunications network is needed to allow for enhanced detection and surveillance of high-risk pathogens, improved capacity of healthcare professionals to implement infection prevention and control protocols and strengthened outbreak response capabilities.

INTERVENTION

Apply telehealth concepts to outbreak preparation

TYPE OF ACTIVITIES 

Surveillance

APPROXIMATE FUNDING NEED

$2.3 million

Vietnam

NEED

Unpublished AMR surveillance data show carbapenem resistance to be highly endemic in Vietnam and an urgent threat to public health.

INTERVENTION

Establish a national AMR surveillance system to strengthen Vietnam’s ability to improve response to resistant infections and improve patient safety

TYPE OF ACTIVITIES 

Surveillance

APPROXIMATE FUNDING NEED

$2.6 million

Haiti

NEED

While great strides have been made in Haiti’s ability to detect diseases and support a One Health approach, additional support for the national surveillance program is needed to ensure sustainability for priority diseases.

INTERVENTION

Support infectious disease investigations by strengthening the national and departmental/site-level surveillance programs, including the HIV/AIDS integrated case-based surveillance system

TYPE OF ACTIVITIES 

Surveillance

APPROXIMATE FUNDING NEED

$4.1 million

Funding Needed
$11,100,000
Surveillance
Nigeria
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Immunization

Immunization

Vaccines prevent an estimated 2.5 million deaths among children younger than age five every year. Still, one child dies every 20 seconds from a disease that could have been prevented by a vaccine. Why? Because one in five children in the world does not have access to the lifesaving immunizations that keep children healthy.

CDC is involved in one of the most effective of all global public health missions—vaccination against deadly diseases, which saves the lives of two to three million people every year. CDC works closely with a wide variety of partners to protect global citizens against contagious and life-threatening vaccine-preventable diseases.

Nigeria

NEED

Nigeria is hyper-endemic for hepatitis B virus (HBV) infection, with an overall population prevalence of chronic HBV infection of 12.2 percent (an estimated 20 million persons).

INTERVENTION

Improve timely hepatitis B birth dose vaccination in key Nigerian states

TYPE OF ACTIVITIES 

Immunization

APPROXIMATE FUNDING NEED

$2.7 million

Vietnam

NEED

There is a need to enhance Vietnam’s major immunization policy authorities for greater independence and technical expertise focused on linking decision-making to scientific evidence.

INTERVENTION

Strengthen the evidence-based decision-making capacity of national immunization policy authorities


Increase demand for and usage of existing, routinely recommended immunizations


Build economic analysis and financial planning capacity in the national immunization program


Strengthen sub-national capacity for surveillance and data management of vaccine-preventable diseases

TYPE OF ACTIVITIES 

Immunization

APPROXIMATE FUNDING NEED

$2.1 million

Funding Needed
$4,800,000
immunization
Nigeria
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Vietnam

Vietnam

In partnership with CDC, the CDC Foundation seeks to strengthen the ability of the Ministry of Health in Vietnam to detect, respond and prevent outbreaks that threaten both the population of the country and world. This includes activities to strengthen influenza preparedness, improve advanced diagnostic laboratory capacity, strengthen the epidemiological workforce, improve antimicrobial resistance (AMR) surveillance and antibiotic use, expand health care service delivery for tuberculosis (TB) and improve immunization delivery. Specific public-private partnership resource needs in Vietnam include:

Disease Focus–Influenza

NEED

Vietnam is at high risk for emerging influenza viruses with pandemic potential.

INTERVENTION

Strengthen the surveillance system for Severe Viral Pneumonia, the primary system for detection of novel influenza viruses and other emerging respiratory pathogens in humans


Estimate the economic burden of influenza in Vietnam


Introduce seasonal flu vaccine and implement national scale up

TYPE OF ACTIVITIES 

Disease specific (Influenza)

APPROXIMATE FUNDING NEED

$3.8 million

Workforce Development–Epidemiology Training

NEED

Key to addressing the challenges of outbreak detection, prevention and response in Vietnam is the development of a public health workforce with solid practical epidemiological skills.

INTERVENTION

Expand the Field Epidemiology Training Program in Vietnam

TYPE OF ACTIVITIES 

Workforce development

APPROXIMATE FUNDING NEED

$1.6 million

Immunization–Policy Enhancement

NEED

There is a need to enhance Vietnam’s major immunization policy authorities for greater independence and technical expertise focused on linking decision-making to scientific evidence.

INTERVENTION

Strengthen the evidence-based decision-making capacity of national immunization policy authorities


Increase demand for and usage of existing, routinely recommended immunizations


Build economic analysis and financial planning capacity in the national immunization program


Strengthen sub-national capacity for surveillance and data management of vaccine-preventable diseases

TYPE OF ACTIVITIES 

Immunization

APPROXIMATE FUNDING NEED

$2.1 million

Laboratory–Reference Labs

NEED

The ministry of health has limited capacity to detect unusual or emerging pathogens in the course of outbreak investigations.

INTERVENTION

Establish a national public health reference laboratory network with the capacity for advanced diagnostic testing that produces credible results

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$1.2 million

Surveillance–Antimicrobial Resistance

NEED

Unpublished AMR surveillance data show carbapenem resistance to be highly endemic in Vietnam and an urgent threat to public health.

INTERVENTION

Establish a national AMR surveillance system to strengthen Vietnam’s ability to improve response to resistant infections and improve patient safety

TYPE OF ACTIVITIES 

Surveillance

APPROXIMATE FUNDING NEED

$2.6 million

Disease Focus–Tuberculosis

NEED

Among 30 high-burden TB countries in the world, Vietnam ranks sixteenth, with an estimated 124,000 new TB patients in 2017 alone, including 7,100 cases of multidrug-resistant TB and 12,000 TB-related deaths.

INTERVENTION

Rapidly reduce TB burden in Ho Chi Minh City and other priority provinces through demonstration projects and scale up


Prevent TB among US-bound immigrants and refugees from Vietnam

TYPE OF ACTIVITIES 

Disease specific (TB)

APPROXIMATE FUNDING NEED

$2.3 million

Funding Needed
$13,600,000
Key Facts
Vietnam yearly flu-like illnesses: over 1 million
Vietnam has 17,000 TB deaths annually
70% of U.S. TB cases are among those foreign-born
vietnam
Viet Nam
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Sierra Leone

Sierra Leone

In partnership with the Sierra Leone Ministry of Health and Sanitation, the CDC Foundation and CDC seek to maintain and build upon critical capacities developed during the 2014–2016 Ebola outbreak in West Africa. Specific public-private partnership resource needs in Sierra Leone include:

Laboratory–Public Health Lab

NEED

Renovations, equipment, supplies and workforce development are needed for the Central Public Health Laboratory (CPHRL) to serve the five reference laboratories within Sierra Leone and provide leadership and guidance within the MOHS public health systems.

INTERVENTION

Sustainably renovate and operationalize the CPHRL

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$2 million

Emergency Preparedness–Ebola Database

NEED

Preserving the informational legacy of the Ebola epidemic gives a unique opportunity to analyze the mortality impact of Ebola, improve future Ebola responses and build research capacity in Sierra Leone.

INTERVENTION

Improve secure access to the Sierra Leone Ebola Database

TYPE OF ACTIVITIES 

Emergency preparedness

APPROXIMATE FUNDING NEED

$900,000

Emergency Preparedness–Emergency Operations Center

NEED

Operational support of the National EOC will cease in June 2019 and additional planning is needed to ensure this support is successfully transitioned to the MoHS.

INTERVENTION

Build country ownership for the National Emergency Operations Center

TYPE OF ACTIVITIES 

Emergency preparedness

APPROXIMATE FUNDING NEED

$750,000

Workforce Development–Epidemiology Training

NEED

Currently, the Field Epidemiology Training Program relies on technical support from international mentors to maintain program quality.

INTERVENTION

Strengthen the Field Epidemiology Training Program so that graduates can serve as mentors for future cohorts

TYPE OF ACTIVITIES 

Workforce development

APPROXIMATE FUNDING NEED

$3.1 million

Disease Focus–Malaria

NEED

Indoor bites from mosquitoes account for 80%–100% of overnight malaria transmission in Africa, and while built-environment modifications were once staples of malaria vector control, they have been neglected for at least the past two decades.

INTERVENTION

Implement a pilot study to assess the impact of new screening strategies on malaria vector control

TYPE OF ACTIVITIES 

Disease specific (Malaria)

APPROXIMATE FUNDING NEED

$232,000

Funding Needed
$6,982,000
Key Facts
Malaria: leading cause of death in Sierra Leone
3,900 deaths during Sierra Leone’s Ebola outbreak
$120M:CDC/CDC Foundation Ebola response investment
sierra leone
Sierra Leone
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Haiti

Haiti

In partnership with the Government of Haiti, CDC seeks to strengthen and further the significant but fragile global health security gains made in Haiti through CDC’s post-earthquake support, set to end in Fiscal Year 2020. Specific public-private partnership resource needs in Haiti include:

Surveillance–Disease Investigations

NEED

While great strides have been made in Haiti’s ability to detect diseases and support a One Health approach, additional support for the national surveillance program is needed to ensure sustainability for priority diseases.

INTERVENTION

Support infectious disease investigations by strengthening the national and departmental/site-level surveillance programs, including the HIV/AIDS integrated case-based surveillance system

TYPE OF ACTIVITIES 

Surveillance

APPROXIMATE FUNDING NEED

$4.1 million

Laboratory–Capacity Building

NEED

In order to accurately identify and detect pathogens, Haiti’s laboratory quality systems need improvement.

INTERVENTION

Improve pathogen detection by building public health laboratory capacity through expansion of Haiti’s specimen storage, operationalizing the country’s National Specimen Referral Network and building national and subnational laboratory capacity

TYPE OF ACTIVITIES 

Laboratory

APPROXIMATE FUNDING NEED

$2.9 million

Workforce Development–Epidemiology Training

NEED

Improve Haiti's public health workforce capacity in business administration to ensure proper management of public health projects.

INTERVENTION

Support the Field Epidemiology Training Program and provide community health workers with surveillance training and training in business management software

TYPE OF ACTIVITIES 

Workforce development

APPROXIMATE FUNDING NEED

$4.6 million

Emergency Preparedness–Operations Center

NEED

Hit by multiple natural disasters over the past decade, preparedness and emergency response capacity are critical in Haiti.

INTERVENTION

Fully operationalize an Emergency Operations Center in Haiti by finalizing interoperability of information technology and purchasing equipment, developing table top exercises and continuing training of EOC personnel

TYPE OF ACTIVITIES 

Emergency preparedness

APPROXIMATE FUNDING NEED

$464,000

Disease Focus–Cholera

NEED

While Haiti is recording the lowest levels of suspected cholera cases since 2011, cholera remains a public health threat and gains made since the last outbreak must be maintained.

INTERVENTION

Interrupt cholera transmission by enhancing Haiti’s laboratory cholera surveillance and response capacity and implementing water, sanitation and hygiene projects

TYPE OF ACTIVITIES 

Disease specific (Cholera)

APPROXIMATE FUNDING NEED

$4.1 million

Disease Focus–Lymphatic Filariasis

NEED

Lymphatic filariasis is on the cusp of elimination in Haiti, one of only four countries in the Americas where the disease remains.

INTERVENTION

Eliminate lymphatic filariasis through mass drug administration, morbidity management and disability prevention and surveillance

TYPE OF ACTIVITIES 

Disease specific (Neglected tropical disease)

APPROXIMATE FUNDING NEED

$15 million

Funding Needed
$31,164,000
Key Facts
1 of 4 areas in Americas with lymphatic filariasis
140K-180K: HIV-positive people in Haiti in 2018
Over 9,000 cholera deaths in Haiti since 2010
haiti
Haiti
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