To assess the acceptability, safety, feasibility and cost of a Typhoid Conjugate Vaccine (TCV) delivered as part of a ministry-led campaign in Harare, Zimbabwe. This evaluation will provide lessons learned and recommendations for future use of TCV in outbreak settings, and to inform typhoid control strategies.

To strengthen laboratory surveillance for pneumococcal meningitis and serotyping in India to understand the impact of a pneumococcal conjugate vaccine rollout.

To assist countries with developing costed, funded plans that address the gaps identified by the World Health Organization-led Joint External Evaluation (JEE) process, with the goal of helping countries reach compliance with the International Health Regulations. The CDC Foundation and CDC will support eight countries as they develop draft costed plans and help them identify funding to implement the plans.

To target cohorts of critical district-level leaders and health officials in Uganda, aiming to harmonize the curricula for District Emergency Response activation with the frontline Field Epidemiology Training Program, while strengthening their respective surveillance components. This effort will incorporate both animal and human disease reporting, case management, infection prevention and control, practices to contain outbreaks at the source, electronic sample tracking and shared animal and human health surveillance and response data communications.

To strengthen the global evidence base of the management of cardiovascular diseases; improve point-of-care testing; and monitor trends within the global noncommunicable disease burden.

To evaluate water treatment and water, sanitation and hygiene (WASH) practices in clinics and schools in Kenya.

To implement a two-phased approach to provide short and long-term solutions to the problem of inadequate water, sanitation and hygiene infrastructure in low-resource settings in Burkina Faso, Ethiopia, Ghana and Uganda.

To promote technical exchange through establishment and improvement of public health surveillance systems, laboratory testing and training to enhance public health initiatives related to cardiovascular disease.

To develop a shared measurement system to monitor impact, progress and outcomes of the Better Hearts Better Cities Urban Health Initiative for Hypertension across three intervention sites using tools developed by the Global Hearts Initiative.

To develop a white paper to identify where investments could best promote the development of the tools needed to enable the more effective use of next-generation sequencing in public health and to prioritize areas where further development would be most impactful.