To evaluate the feasibility, impact and safety of RTS,S/AS01E malaria vaccine implementation through routine health systems in moderate to high malaria transmission settings in sub-Saharan Africa.

To support cryopreservation and suppression of female development in mosquitoes to assist research for malaria control.

To support a mosquito stock repository that supplies living and preserved laboratory cultured malaria-vector mosquitoes to researchers studying malaria.

To strengthen vaccine-preventable disease surveillance platforms to maximize their capacity to measure burden of disease and to monitor the impact of vaccines. Activities include improving immunization data quality; evaluating impact and implementation of vaccines (including oral cholera, rubella, and HPV); improving the quality and planning of measles and rubella campaigns; and strengthening surveillance for vaccine preventable diseases (meningitis, diphtheria and pertussis, intussusception).