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Partnering for Vaccine Equity

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COVID vaccination
Partnering for Vaccine Equity
United States of America
To increase vaccine confidence, access and acceptance among adults, especially in communities that have been marginalized by long-standing health and social inequities.
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Evaluating HPV Vaccine Induced Antibodies in Botswana

1176
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infectious disease
Evaluating HPV Vaccine Induced Antibodies in Botswana
Botswana
To evaluate the impact of HPV vaccine and the persistence of HPV antibody among HPV-vaccinated women living with HIV in Botswana.
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Support for Inactivated Rotavirus Vaccine

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infectious disease
Support for Inactivated Rotavirus Vaccine
United States of America
To support the chemistry, manufacturing and control (CMC) and preclinical development of an inactivated rotavirus vaccine.
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Enhancing Community Acceptance of Syringe Services Programs

The United States is in the midst of a growing opioid epidemic. As a result of sharing contaminated needles, HIV transmission rates have also increased. In response, the Centers for Disease Control and Prevention (CDC) is providing tools that can reduce harm in communities experiencing high rates of HIV transmitted by needles. Syringe Services Programs (SSPs) can support communities by offering services such as testing for HIV and other infectious diseases, access to clean needles and connection to treatment upon request. Unfortunately, there is a significant stigma surrounding SSPs and the people who use them. This project aims to leverage social media to educate communities about the benefits of SSPs, dispel misinformation and garner support at a grassroots level. CDC is funding the CDC Foundation to implement public health interventions based on social media messaging and engagement in target communities. The CDC Foundation is partnering with the Public Good Projects (PGP), a nonprofit with expertise in implementing public health interventions on social media.

41122
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infectious disease
United States of America
To leverage social media to educate communities about the benefits of Syringe Services Programs, dispel misinformation and garner support at a grassroots level. Syringe Services Programs can support communities by offering services such as testing for HIV and other infectious diseases, clean needles, and connection to treatment upon request.
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Pathogenic Paramyxovirus Replication in BSL-4 Containment

1168
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infectious disease
Pathogenic Paramyxovirus Replication in BSL-4 Containment
United States of America
To develop cell culture and small animal models of Nipah virus replication and pathogenesis in a biosafety level (BSL) 4 lab.
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Field Epidemiology Training Program (FETP) in Qatar

1167
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infectious disease
Field Epidemiology Training Program (FETP) in Qatar
Qatar
To assist the Ministry of Public Health (MOPH) in establishing a Field Epidemiology Training Program (FETP) in Qatar focused on building its public health workforce capacity.
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Investigating Safety and Efficacy of L9LS Monoclonal Antibodies in Western Kenya

1164
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infectious disease
Investigating Safety and Efficacy of L9LS Monoclonal Antibodies in Western Kenya
Kenya
To investigate other novel interventions, such as monoclonal antibodies (MAbs) against malaria. An intervention that could prevent malaria in children for a full 12 months in settings of perennial malaria transmission, such as Kenya, holds potential to reduce malaria morbidity and mortality substantially in this population at risk for severe malaria and death.
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Improving Water, Sanitation & Hygiene Services in Healthcare Facilities

The CDC Foundation is collaborating with the Centers for Disease Control and Prevention (CDC) to expand best practices for water, sanitation and hygiene (WASH) in healthcare facilities (HCFs) through implementation of targeted action research pilots in Uganda. These pilots involve developing and testing context-appropriate solutions for increasing uptake of WASH practices and sustained management of WASH services that meet the needs of patients and healthcare workers. Proposed action pilots will adapt promising interventions implemented in the United States and other healthcare settings to the context of Ugandan primary HCFs or identify new approaches where no interventions exist.

Pilot activities will include:

  • Identifying the determinants of sustainability of WASH infrastructure in HCFs through review of policies and practices among HCFs with well and poorly managed infrastructure;
  • Understanding patient and healthcare worker needs for drinking water and sanitation services, which remain understudied, and testing systems that meet their needs;
  • Assessing the effectiveness and acceptability of formalizing management responsibilities of WASH infrastructure that is often neglected, such as water supply and sanitation facilities, through standard operating procedures and job aids;
  • Identifying and testing culturally appropriate accountability systems for improving healthcare worker hand hygiene practices, including novel approaches that are suitable for small facilities.

There has been increased global focus in the past decade on the inadequate status of systems and WASH practices in HCFs and the importance of these systems for preserving the health and dignity of healthcare workers, patients and communities. Recent Ebola outbreaks and the COVID-19 pandemic have further highlighted the essential role of strong WASH systems in HCFs for infection prevention and control (IPC). However, despite advocacy and intervention efforts, global WASH in HCF stakeholder meetings in 2016 and 2019 continued to find significant gaps in sector knowledge. These include the need to identify effective approaches for sustainably managing WASH services and ensuring appropriate WASH practices are consistently adopted, particularly in aspects of patient and staff WASH needs that lie outside of IPC such as drinking water and sanitation.

As an increasing number of partners engage in WASH in HCF initiatives, evidence-based, field-tested best practices in these areas are needed to enable effective implementation and management by HCF leadership and supporting partners.

1162
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infectious disease
Improving Water, Sanitation & Hygiene Services in Healthcare Facilities
Uganda
To expand CDC’s strategic engagement in learning and evaluation of best practices for water, sanitation and hygiene (WASH) in health care facilities through implementation of targeted action research pilots in Uganda.
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Microbicide Research and Development to Advance HIV Prevention Technologies through Responsive Innovation and eXcellence (MATRIX)

1161
MATRIX
United States of America
To evaluate a novel intravaginal ring to prevent HIV infection combined with a contraceptive to prevent unintended pregnancy. MATRIX stands for Microbicide Research and Development to Advance HIV Prevention Technologies through Responsive Innovation and eXcellence.
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Rotavirus Vaccine Impact and Effectiveness Assessments

1159
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infectious disease
Rotavirus Vaccine Impact and Effectiveness Assessments
Burkina Faso
Democratic Republic of the Congo
To ensure impact and effectiveness of rotavirus vaccines and sustain vaccine use by policy makers, physicians and parents to increase the speed of adoption of vaccine by other countries in Africa and around the world.
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