Enhancing Community Acceptance of Syringe Services Programs

The United States is in the midst of a growing opioid epidemic. As a result of sharing contaminated needles, HIV transmission rates have also increased. In response, the Centers for Disease Control and Prevention (CDC) is providing tools that can reduce harm in communities experiencing high rates of HIV transmitted by needles. Syringe Services Programs (SSPs) can support communities by offering services such as testing for HIV and other infectious diseases, access to clean needles and connection to treatment upon request. Unfortunately, there is a significant stigma surrounding SSPs and the people who use them. This project aims to leverage social media to educate communities about the benefits of SSPs, dispel misinformation and garner support at a grassroots level. CDC is funding the CDC Foundation to implement public health interventions based on social media messaging and engagement in target communities. The CDC Foundation is partnering with the Public Good Projects (PGP), a nonprofit with expertise in implementing public health interventions on social media.

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infectious disease
United States of America
To leverage social media to educate communities about the benefits of Syringe Services Programs, dispel misinformation and garner support at a grassroots level. Syringe Services Programs can support communities by offering services such as testing for HIV and other infectious diseases, clean needles, and connection to treatment upon request.
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CDC Foundation Supports 53 Community-Based Organizations to Implement and Expand HIV Self-Testing Programs

According to the Centers for Disease Control and Prevention (CDC), one in eight people living with HIV in the United States is undiagnosed, and more than one third of all new HIV infections are transmitted by people who do not know that they have HIV. Community-based organizations will help increase access to HIV self-testing in underserved communities and among those most vulnerable to HIV.

Microbicide Research and Development to Advance HIV Prevention Technologies through Responsive Innovation and eXcellence (MATRIX)

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MATRIX
United States of America
To evaluate a novel intravaginal ring to prevent HIV infection combined with a contraceptive to prevent unintended pregnancy. MATRIX stands for Microbicide Research and Development to Advance HIV Prevention Technologies through Responsive Innovation and eXcellence.
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Home-Based PrEP for Youth

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Home-Based PrEP for Youth
United States of America
To evaluate a model of oral HIV pre-exposure prophylaxis (PrEP) implementation for youth that includes home PrEP (with fewer in-person clinic visits and a telemedicine approach). The objective is to evaluate the safety, acceptability of and adherence to home-based daily oral PrEP among young men who have sex with men and transgender women.
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World AIDS Day—New Strategy Aims to Take on Cryptococcal Meningitis, Which Threatens Those With HIV

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Evaluating Tuberculosis Preventive Treatment in People Living with HIV

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PROTECT logo

The CDC Foundation is collaborating with CDC to implement the Preventing Occurrence of Tuberculosis by Expanding Coverage of Tuberculosis Preventive Treatment among People Living with HIV (PROTECT). With funding from the Bill & Melinda Gates foundation, the CDC Foundation is working with CDC’s Division of Global HIV and Tuberculosis to evaluate the overall impact of the scale-up of Tuberculosis Preventive Therapy (TPT) on tuberculosis incidence and mortality among people living with HIV (PLHIV).

Tuberculosis (TB) remains the leading cause of morbidity and mortality among PLHIV. Despite advances in global HIV care and treatment and an extensive body of literature demonstrating the efficacy of TPT and antiretroviral therapy (ART) in PLHIV and the benefits of receiving both drugs in reducing TB-related morbidity and mortality, global scale-up of TPT has been minimal. In 2018, when TB accounted for one-third of all HIV-related deaths, the President’s Emergency Plan for AIDS Relief (PEPFAR) committed to providing at least one course of TPT to all 14.6 million PLHIV in care within three years. Though progress has been made towards that goal, with CDC providing technical assistance to several countries and their ministries of health, the overall impact of widescale TPT implementation in program settings on TB incidence and mortality is not known.

PROTECT will be implemented in six countries; three retrospective countries (Nigeria, Kenya, Ukraine) that already scaled up TPT among PLHIV and three prospective countries (Haiti, Uganda, Zimbabwe) that are currently scaling up TPT among PLHIV.

This project aims to achieve the following objectives:

  1. To describe TB incidence at 12 months and 24 months among PLHIV who have initiated TPT versus those who did not initiate TPT; and
  2. To describe all-cause mortality at 12 months and 24 months among PLHIV who have initiated TPT versus those who did not initiate TPT.

This project draws on CDC’s expertise in TB surveillance and program evaluation, as well as its strong partnerships with countries and global partners. CDC and participating countries will share lessons learned and best practices with countries scaling up TPT for PLHIV through project-specific workshops and existing networks. Countries will work closely with CDC to share results in-country to guide program decisions and disseminated to the global community through abstracts, manuscripts, and other opportunities.

Read our recent blog highlighting the work we're doing to combat tuberculosis.

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global health
Evaluating Tuberculosis Preventive Treatment in People Living with HIV
Haiti
Kenya
Nigeria
Ukraine
Uganda
Zimbabwe
To determine the impact of Tuberculosis preventative treatment among populations living with HIV.
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HIV Prevention Trials Network

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Red Ribbon
HIV Prevention Trials Network
Thailand
To evaluate the efficacy of injectable pre-exposure prophylaxis (PrEP) for HIV-uninfected cisgender men and transgender women who have sex with men.
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HIV Epidemic Fund

The Ending the HIV Epidemic Fund

We have a unique, once-in-a-generation opportunity to leverage data, scientific tools and technology to eliminate HIV in the United States by 2030. The national initiative Ending the HIV Epidemic: A Plan for America is focused on the highest burden 48 counties, Washington, D.C., and San Juan, Puerto Rico, as well as seven states with the highest rural HIV burden. These jurisdictions together account for more than 50 percent of new HIV diagnoses in recent years.

The U.S. Department of Health and Human Services (HHS) is leading the End of the HIV Epidemic initiative. This plan aims to reduce the number of new HIV diagnoses by at least 90 percent within 10 years.

Importantly, this plan will leverage scientific advances in HIV prevention, diagnosis, treatment and care by coordinating the highly successful programs, resources and technical expertise of the Centers for Disease Control and Prevention (CDC) and other HHS agencies.

Success requires the involvement of the public, philanthropic and private sectors. The CDC Foundation’s Ending the HIV Epidemic Fund is designed to build on and extend public funding, enabling individual and organizational donors to support this historic opportunity to eliminate HIV in the United States.

Digital Education Strategy and Campaign

Need

It can be difficult to reach audiences most susceptible to HIV with effective messaging.

Intervention

Develop innovative digital campaigns to reach those living with and most vulnerable to HIV, in coordination with state and local partners, for maximum impact.

Type of Activities

Campaigns to increase diagnosis, link people to treatment, prevent HIV transmission, and respond quickly to outbreaks.

Approximate Funding Need

Funding needs are variable depending on specific activity.

Innovative Models of Community Care

Need

While traditional care approaches work for reaching some communities, reaching all those most vulnerable will require disruptive, innovative approaches.

Intervention

Design care delivery systems that deliver comprehensive, evidence-based prevention and treatment services, including support for syringe services programs.

Type of Activities

Prevention

Approximate Funding Need

Funding needs are variable depending on specific activity.

Rural Access to Treatment and Care

Need

Many rural communities lack sufficient access to preventive healthcare services, including PrEP, and HIV testing in their locations.

Intervention

Expand opportunities for care in rural communities by mobilizing and promoting programing and technologies such as community-based pharmacies, home-based HIV testing, and greater utilization of telemedicine.

Type of Activities

Linkage to Care

Approximate Funding Need

Funding needs are variable depending on specific activity.

Key Facts
2030 is the target for eliminating HIV in America
Plan aims to reduce HIV diagnoses 75% in 5 years
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HIV
United States of America
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Cryptococcal Screening and Treatment Continuation

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Infectious Disease
Botswana
Rwanda
Tanzania
To continue implementation of a cryptococcal meningitis screen and treat program in the nine African countries to preemptively treat patients and avoid potential infection or death.
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