To conduct targeted assessments involving vaccine research and surveillance. The current studies range from a meningitis carriage study in Burkina Faso to measure the impact of the MenA vaccine, to rotavirus surveillance in Mozambique to look at vaccine effectiveness.
Davycas International, Fundaҫão Manhiҫa, Ministry of Health Haiti, Norwegian Institute of Public Health, World Health Organization, London School of Hygiene and Tropical Medicine
To provide a comprehensive literature search on Pneumococcal Conjugate Vaccine impact on immunogenicity, nasopharyngeal colonization, otitis media, pneumonia, invasive pneumococcal disease and mortality.
Johns Hopkins University (Bill & Melinda Gates Foundation)
CDC’s National Center for Immunization and Respiratory Diseases; Johns Hopkins Bloomberg School of Public Health; International Vaccine Access Center; World Health Organization
To support an immunization and chade Beaumontllenge trial of CDC's P. falciparum chimeric MSP1/8 vaccine in nonhuman primates. The specific model will involve studies in the monkey species Aotus nancymaae using the P. falciparum FVO strain.
To help CDC contribute to research about genetic changes in pneumococcal bacteria that impact the effectiveness of vaccination in developing countries. CDC will provide isolates from their Global Pneumococcal Strain Bank, sequence isolates from the Active Bacterial Core surveillance collaboration, and provide expert guidance on analysis and interpretation of the data.
Emory University (Gates Foundation)
CDC’s National Center for Immunization and Respiratory Diseases
To initiate a network of South African hospitals to conduct intussusception surveillance and apply the resource-efficient and scientifically sound case-series analysis to generate vital evidence for monitoring the safety of rotavirus vaccine use.
Bill & Melinda Gates Foundation
CDC’s National Center for Immunization and Respiratory Diseases; University of Witwatersrand