To conduct an evaluation of N. Meningitidis and N. Lactamica in Burkina Faso as part of a larger initiative to introduce a novel serogroup A conjugate meningococcal vaccine in Africa and eliminate epidemic meningitis.

To provide technical assistance to the monitoring and evaluation of a cryptococcal screening program in partnership with the South African government. Cryptococcal meningitis is a common infection and a leading cause of death among individuals with HIV/AIDS.

To establish a regional surveillance network—MenAfriNet—to collect and analyze high quality case-based meningitis surveillance data from representative sites across the African meningitis belt. The meningitis surveillance network will evaluate the impact of MenAfriVac to guide research on new vaccines and strategies to optimize impact of existing vaccines.