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CDC’s National Report on Human Exposure to Environmental Chemicals provides an ongoing assessment of the U.S. population’s exposure to 148 different environmental chemicals. |
The places where people live, work and play can greatly impact their health. CDC conducts research that analyzes to what extent these possible environmental threats affect our health and who may be most at risk. The CDC Foundation helps CDC collaborate with universities and research institutions in the U.S. and around the world to investigate potential environmental health threats and make recommendations for how to mitigate their affects on our health.
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Featured Program:
Foundation Partnership Helps Improve Hormone Measurement
Results from the multi-year project, which is funded by Solvay Pharmaceuticals, Inc. and involves scientists at CDC and Boston Medical Center (BMC), will help clinicians better diagnose and manage hormone-related diseases, such as hypogonadism in men. Read more |
Environmental Health Programs
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Advanced Reproductive Age and Environmental Health
To determine the risk of asthma in children as a result of PAH-related air pollutant exposure as a means to intervene in the development of the disease.
- Funding Partners: Mount Sinai School of Medicine
- Program Partners: National Center for Environmental Health, CDC
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Air Pollution and Asthma in Children
To determine the risk of asthma in children as a result of PAH-related air pollutant exposure as a means to intervene in the development of the disease.
- Funding Partners: Columbia Center for Children's Environmental Health
- Program Partners: National Center for Environmental Health, CDC
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Asia-Pacific Smoking Study
To determine if smokers of charcoal filtered cigarettes have lower mouth-level exposure to volatile organic compounds (VOCs) and if a lower mouth-level exposure results in lower biomarkers of exposure.
- Funding Partners: University of Waterloo
- Program Partners: National Center for Environmental Health, CDC
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Avon Longitudinal Study of Pregnancy and Childhood
To analyze maternal blood samples from the University of Bristol, England, for mercury, lead, cadmium and selenium to assess the interactions of these chemicals on the neurological development, academic performance, behavioral outcomes and IQ of the child.
- Funding Partners: University of Southern Mississippi
- Program Partners: National Center for Environmental Health, CDC
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Biomonitoring and the Northern California Childhood Leukemia Study
An investigation of potential environmental, dietary and genetic causes of childhood leukemia in the 35 counties of northern and central California.
- Funding Partners: University of California, Berkeley
- Program Partners: National Center for Environmental Health, CDC
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Concentrations of Polybrominated Diphenyl Ethers in Human Milk
To evaluate the lifestyle and demographic factors that contribute to the levels of polybrominated diphenyl ethers (PBDEs) in human milk.
- Funding Partners: Penn State University
- Program Partners: National Center for Environmental Health, CDC
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Cyanides' Role in Smoke Inhalation Study (CRISIS-1)
To survey blood cyanide and urine thiocyanate levels in people who are victims of smoke inhalation.
- Funding Partners: Dey, L.P.
- Program Partners: National Center for Environmental Health, CDC
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Detecting TB Among U.S. Air Force Trainees
To provide technical consultation and support for a larger project designed to assess the feasibility and potential impact of using an automated whole-blood interferon-gamma release assay, referred to as the Automated QuantiFERON®-TB Gold In-Tube Test.
- Funding Partners: U.S. Air Force
- Program Partners: National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, CDC
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Development and Evaluation of Ultrafiltration Methods
To analyze and develop water filtration techniques that may benefit water utility services in Clayton and Gwinnett counties in Georgia.
- Funding Partners: The Rollins School of Public Health of Emory University
- Program Partners: National Center for Zoonotic, Vector-borne and Enteric Diseases, CDC
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Endocrine Disruptors and the Male Reproductive System
To study the influence of prenatal exposure to phthalates and bisphenol A (BPA) on the occurrence of genital abnormalities, specifically cryptorchidism and hypospadias, in the French general population.
- Funding Partners: National Institute of Health and Medical Research, France
- Program Partners: National Center for Environmental Health, CDC
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Endocrine Altering Chemicals and Birth Outcomes
To study the impact of environmental exposure to synthetic endocrine disruptors on intrauterine life, generational changes in gene pattern expression and birthweight as markers of disease risk.
- Funding Partners: Harvard University Medical School
- Program Partners: National Center for Environmental Health, CDC
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Energy Balance, PCB Exposure and Possible Health Effects
To assess the effect of a 12-month exercise and/or diet intervention on polychlorinated biphenyls (PCBs) and investigate whether changes in weight or body composition are correlated with concurrent changes in PCBs.
- Funding Partners: University of Washington
- Program Partners: National Center for Environmental Health, CDC
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Environmental and Genetic Determinants of Puberty
To examine the roles of environmental chemical exposures and genetic susceptibility factors in the early onset of puberty, as a risk factor for breast cancer development.
- Funding Partners: Mount Sinai School of Medicine
- Program Partners: National Center for Environmental Health, CDC
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Environmental Chemicals and Congenital Hearing Loss
To evaluate the prevalence of prenatal exposures to environmental chemicals and whether high levels of exposure may result in hearing deficiencies at birth.
- Funding Partners: University of Oklahoma Health Sciences Center
- Program Partners: National Center for Environmental Health, CDC
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Environmental Chemicals and Lactation
To determine the concentrations of selected phthalates and phenol metabolites in milk samples from the Cincinnati Children's Research Human Milk Bank.
- Funding Partners: Cincinnati Children's Hospital Medical Center
- Program Partners: National Center for Environmental Health, CDC
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Environmental Legionella Recovery Proficiency Testing Program
To help prevent the transmission of Legionnaires’ disease by improving the ability of commercial and reference laboratories to identify and isolate Legionella bacteria in environmental samples.
- Funding Partners: Arch Chemicals, Inc.
- Program Partners: National Center for Environmental Health, CDC
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Folate, Diet, DNA Repair Genes and Breast Cancer
To explore the relationship between diet and breast cancer risk by assessing the interaction of dietary and circulating biomarkers of folate, vitamin B-12 and vitamin B-6 with specific DNA repair genes.
- Funding Partners: University of California, Irvine
- Program Partners: National Center for Environmental Health, CDC
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Folate Status and Obesity in African-American Women
To examine the role of obesity and folate metabolic status in African-American women.
- Funding Partners: M.D. Anderson Cancer Center
- Program Partners: National Center for Environmental Health, CDC
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Homocysteine Method Comparison Study
To examine how current clinical methods perform to provide important insight about the comparability of methods used to measure homocysteine levels in clinical laboratories. Studies indicate that elevated levels of the amino acid homocysteine are related.
- Funding Partners: ARUP Laboratories
- Program Partners: National Center for Environmental Health, CDC
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Human Exposure to Perchlorate from Vegetables and Grains
To learn more about how humans may be exposed to perchlorate, a thyroid-inhibiting anion that is used as a component of solid rocket fuel, explosives and pyrotechnics.
- Funding Partners: University of Arizona Yuma Agricultural Center
- Program Partners: National Center for Environmental Health, CDC
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Indicators of Gestational Exposure to Endocrine Disruptor Substances
- Funding Partners: University of Medicine & Dentistry of New Jersey
- Program Partners: National Center for Environmental Health, CDC
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Investigating Children's Exposure to PBDEs
To examine the health consequences of children's exposure to polybrominated diphenyl ethers (PBDEs) in a longitudinal birth cohort study investigating exposure to environmental toxicants and children's health in Salinas Valley, Monterey County, California.
- Funding Partners: University of California, Berkeley
- Program Partners: National Center for Environmental Health, CDC
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Jet Fuel Exposure in Military Personnel
To measure human urine and blood samples for levels of polycyclic aromatic hydrocarbon (PAH) metabolites and volatile organic compounds (VOCs) to examine the relationship between jet fuel exposure and adverse neurological outcomes in military personnel.
- Funding Partners: Henry M. Jackson Foundation for the Advancement of Military Medicine, The United States Army
- Program Partners: National Center for Environmental Health, CDC
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Levels of PAC and PAC Metabolites in Paving Workers
To determine the optimized time to collect samples from paving workers and ensure analytical methods to identify asphalt fume exposures in workers involved in hot-mix asphalt paving operations.
- Funding Partners: Asphalt Refining Company, Heritage Research Group
- Program Partners: National Center for Environmental Health, CDC
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Maternal Exposure to Environmental Chemicals
To assess maternal exposure to brominated flame retardants (BFRs), polychlorinated biphenyls (PCBs), organochlorine pesticides and polycyclic aromatic hydrocarbons (PAHs). This pilot study will provide information needed for future health studies.
- Funding Partners: Health Canada
- Program Partners: National Center for Environmental Health, CDC
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Measuring Acrylanide Biomarkers: Nurses Health Study II
To assess human exposure to acrylanide (a suspected human carcinogen found in tobacco smoke, fried foods and certain industrial processes) by measuring samples from a subset of the Nurses Health Study.
- Funding Partners: Harvard School of Public Health
- Program Partners: National Center for Environmental Health, CDC
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Measuring PAHs in a Cohort of NYC Women and Children
To evaluate whether exposure to PAHs during pregnancy adversely affects fetal development, asthma development and child health.
- Funding Partners: Columbia University
- Program Partners: National Center for Environmental Health, CDC
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Menthol, Ethnicity and Nicotine Dependence
To examine the relationship of menthol levels in cigarettes, specific smoking behaviors and levels of addictiveness and carcinogenic risk. Results from this study are expected to lead to more effective prevention activities.
- Funding Partners: Ohio State University, The Ohio State University Research Foundation
- Program Partners: National Center for Environmental Health, CDC
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Molecular Epidemiology of Multiple Xenoestrogen Exposure
To examine the relationship between xenoestrogen exposure (e.g. alkylphenols, bisphenol A, phthalates, and pyrethroid pesticides) and gene polymorphisms related to hormone receptors and breast cancer.
- Funding Partners: Mount Sinai School of Medicine
- Program Partners: National Center for Environmental Health, CDC
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Michigan PBB Cohort 30 Years Later: Endocrine Disruption
To conduct a reproductive health study of women working and/or living on farms who were exposed directly (and their daughters exposed perinatally) to polybrominated biphenyls (PBBs) that were inadvertently substituted for livestock feed supplement in 1973.
- Funding Partners: Emory University
- Program Partners: National Center for Occupational Safety and Health, CDC
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Neurotoxic Effects of Maneb and Paraquat
To determine whether developmental or adult exposure to a combination of two pesticides, paraquat and maneb, causes neural degeneration in regions of the brain that degenerate in Parkinson's disease.
- Funding Partners: Exponent, Inc.
- Program Partners: National Center for Environmental Health, CDC
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Norovirus In-Vitro Time-Kill Evaluation
To evaluate commercial sanitizing products for their virucidal effectiveness against murine norovirus.
- Funding Partners: Mölnlycke Health Care, LLC; Oxoid Ltd.; Pathcon Laboratories
- Program Partners: National Center for Environmental Health, CDC
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Nutritional Biomarkers of Oxidative Stress
To measure circulating concentrations of fat-soluable micronutrients (retinols, tocopherols, xathophylls and carotenoids) and ferritin, an iron status indicator, in an effort to test new approaches to cancer prediction and prevention.
- Funding Partners: Emory University
- Program Partners: National Center for Environmental Health, CDC
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Osteoarthritis Project
To learn more about the environmental and genetic factors that may lead to the onset or worsening of osteoarthritis of the knees, hips, hands and low back.
- Funding Partners: University of North Carolina at Chapel Hill
- Program Partners: National Center for Environmental Health, CDC
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PCBs, Phthalates and Male Reproductive Health
To determine if and how exposure to PCBs and phthalates affects male fertility.
- Funding Partners: Harvard School of Public Health
- Program Partners: National Center for Environmental Health, CDC
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Perchlorate Analysis in Breast Milk and Urine
To measure perchlorate concentrations in breast milk, urine and drinking water.
- Funding Partners: University of Medicine & Dentistry of New Jersey
- Program Partners: National Center for Environmental Health, CDC
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Perchlorate Content of Eggs
To quantify background levels of perchlorate, nitrate, thiocyanate and iodide in chicken eggs to provide information about dietary exposure to perchlorate and other chemicals.
- Funding Partners: University of California
- Program Partners: National Center for Environmental Health, CDC
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Phthalate Exposure in Pregnant Women Living in New York
To measure levels of phthalate metabolites in urine samples of pregnant women in New York City. Phthalate is a manufactured chemical that is added to plastics, paint, glue, hair spray and other household products and is commonly found in the environment.
- Funding Partners: Columbia University
- Program Partners: National Center for Environmental Health, CDC
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Phthalates in Pregnant Women and Children
To measure the concentration of urinary phthalate metabolites in pregnant women and their children. The study will also examine sources of exposure and links of phthalate levels to alterations in reproductive development.
- Funding Partners: University of Missouri, Columbia
- Program Partners: National Center for Environmental Health, CDC
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Smoking During Pregnancy and Infantile GI Dysregulation
To sample analysis for motilin concentrations performed at CDC/NCEH in support of the Infantile GI Dysregulation project.
- Funding Partners: Brown University, The Miriam Hospital
- Program Partners: National Center for Environmental Health, CDC
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Testosterone Measurement Harmonization
To improve and standardize testosterone measurements to help provide better medical care to people with impaired androgen levels and people receiving androgen therapy.
- Funding Partners: Solvay Pharmaceuticals, Inc.
- Program Partners: National Center for Environmental Health, CDC
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University of Washington Farmers Study
To investigate multiple pathways that may contribute to pesticide exposure in adults and children living in agricultural communities.
- Funding Partners: Fred Hutchinson Cancer Research Center
- Program Partners: National Center for Environmental Health, CDC
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